Laser Assisted Hatching is a cutting-edge technique that is known to improve the chances of successful embryo implantation during IVF and for women who have had previous IVF failures. By facilitating the embryo's escape from its protective shell and enabling it to attach to the uterine lining. The procedure involves using a laser to create an opening or thinning of the zona pellucida or egg shell, around day 3,
or at the blastocyst stage at day 5. The zona pellucida acts as a safeguard by permitting only one embryo to successfully attach while preventing simultaneous attachment of multiple embryos in the uterus
• The indications of Laser assisted hatching can be exemplified and maybe recommended for patients that are advanced over the maternal age (over 35). Also demonstrating the following:
• Elevated levels of follicle-stimulating hormone (FSH)
• Previous IVF procedures where embryos failed to implant (but were otherwise in good health)
• Poor embryo quality
• Embryos exhibiting excessive fragmentation
• Patients with 2 or more previous failed IVF cycles
• Frozen-thawed embryo transfer cycles
Benefits are such that Laser-assisted hatching can help bolster the embryos' ability to implant into the uterine lining, especially in cases where the outer shells of the embryos have hardened
. It may increase the chances of successful implantation and pregnancy in certain individuals.
Risks include Damage to the embryo during laser manipulation
- Increased risk of monozygotic (identical) twinning
- Ovarian hyperstimulation syndrome (OHSS) in cases where ovarian stimulation is used.
• Final considerations should entail that Laser-assisted hatching may not be preferable for every IVF procedure, and several factors should be taken into consideration before recommending it. It is important to consult with a fertility specialist to determine if laser-assisted hatching is appropriate for the specific situation.
It's worth amplifying that different clinics may have variations in their specific protocols and techniques for laser-assisted hatching, therefore each person should investigate each before undertaking the procedure.
