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The Association between assisted reproductive technologies and obesity.

Several studies have investigated the association between assisted reproductive technologies (ART) and obesity. The research indicates that obesity is linked to various negative effects on ART outcomes. Here are some of the conclusions that have been drawn recently from the studies:

Reduced pregnancy and live birth rates have been seen with overweight and obesity undergoing ART. It has been found to have lower pregnancy and/or live birth rates compared to those with lower body mass index (BMI}.

Obesity has been associated with an elevated risk of fertility problems and reduced birth rates following IVF. It has also been linked to anovulation, decreased ovarian attentiveness to ovulatory prescription medications, modified oocyte and endometrial activity, and a greater likelihood of maternal and fetal complications throughout gestation.

In relation to the effect on embryo formation and early development, Overweight/obesity may affect embryo formation and early development, as it has been found to reduce the number of available embryos, high-quality embryo rate, normal fertilization rate, and embryo number.

The fertilization rate is affected in ART procedures, whereby obesity doesn’t seem to significantly affect pregnancy, it does have negative effects on various ART outcomes.

The conclusions that can be interpolated are such that obesity in ART procedures is a viable element that must be carefully examined, if a positive outcome from IVF or related ART is to transpire.

Ref: https://reproductive-health-journal.biomedcentral.com/articles/10.1186/s12978-022-01558-9

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